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Evidence-based guides, score breakdowns & clinical updates

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SOFA · CHA₂DS₂-VASc · Wells PE — all guides in one place

Featured Articles

How to Calculate Wells Score for PE — Pulmonary Embolism Diagnosis Guide
Emergency MedicineFeatured

How to Calculate Wells Score for PE — Pulmonary Embolism Diagnosis Guide

The Wells Score for PE is the global standard for pre-test probability assessment in suspected pulmonary embolism. This complete guide covers every criterion, the D-dimer decision, PERC rule, YEARS algorithm, and the full diagnostic pathway — with a live embedded PE probability calculator.

Dr. Marcus Chen

Dr. Marcus Chen

Emergency Medicine Consultant

April 13, 202515 min read
How to Calculate CHA₂DS₂-VASc Score — AF Stroke Risk & Anticoagulation Guide
CardiologyFeatured

How to Calculate CHA₂DS₂-VASc Score — AF Stroke Risk & Anticoagulation Guide

The CHA₂DS₂-VASc score is the global standard for stroke risk stratification in atrial fibrillation. This complete guide walks through every risk factor, scoring threshold, DOAC selection, and the HAS-BLED counterbalance — with a live embedded AF anticoagulation calculator.

Dr. Sarah Mitchell

Dr. Sarah Mitchell

Interventional Cardiologist

April 13, 202514 min read
How to Calculate SOFA Score Step by Step — With Live Calculator
Critical CareFeatured

How to Calculate SOFA Score Step by Step — With Live Calculator

The SOFA score is the cornerstone of Sepsis-3 diagnosis and ICU organ dysfunction monitoring. This complete guide walks through every variable, scoring threshold, and clinical interpretation — with a live embedded SOFA calculator you can use right now.

Dr. Aisha Rahman

Dr. Aisha Rahman

Intensivist & Emergency Physician

April 13, 202512 min read
Understanding the GRACE Score in Acute Coronary Syndrome: A Practical Guide
CardiologyFeatured

Understanding the GRACE Score in Acute Coronary Syndrome: A Practical Guide

The GRACE score remains the gold standard for risk stratification in ACS. Learn how to apply it at the bedside, interpret results, and translate scores into actionable treatment decisions aligned with ESC 2023 guidelines.

Dr. Sarah Mitchell

Dr. Sarah Mitchell

Interventional Cardiologist

January 18, 20258 min read
The 2021 CKD-EPI Equation: Why Race Was Removed and What It Means for Your Practice
NephrologyFeatured

The 2021 CKD-EPI Equation: Why Race Was Removed and What It Means for Your Practice

The 2021 race-free CKD-EPI equation is now the standard for eGFR estimation. Understand the scientific rationale, clinical implications, and how this change affects drug dosing and CKD staging in your patients.

Dr. James Okonkwo

Dr. James Okonkwo

Consultant Nephrologist

January 14, 20257 min read
SOFA Score and Sepsis-3: A Bedside Guide for Emergency Physicians
Critical CareFeatured

SOFA Score and Sepsis-3: A Bedside Guide for Emergency Physicians

Since Sepsis-3 redefined sepsis using SOFA, every emergency physician needs to master this score. This practical guide covers calculation, interpretation, serial monitoring, and how SOFA drives treatment decisions in the first 6 hours.

Dr. Aisha Rahman

Dr. Aisha Rahman

Intensivist & Emergency Physician

January 10, 202510 min read

All Articles

Wells Score for DVT and PE: When to Use D-Dimer vs. Imaging
Emergency Medicine9 min

Wells Score for DVT and PE: When to Use D-Dimer vs. Imaging

The Wells score is the cornerstone of VTE diagnosis, but knowing when to stop at D-dimer versus proceeding directly to CTPA is where clinical judgment matters most. This guide walks through the complete diagnostic algorithm.

Dr. Marcus Chen

Dr. Marcus Chen

January 7, 2025
NIHSS in Acute Stroke: From Score to Treatment Decision in Under 10 Minutes
Neurology11 min

NIHSS in Acute Stroke: From Score to Treatment Decision in Under 10 Minutes

Time is brain. The NIHSS is your fastest path from clinical assessment to thrombolysis eligibility. Master the 15-item scale, understand the scoring pitfalls, and know exactly which scores unlock which treatments.

Dr. Priya Sharma

Dr. Priya Sharma

January 3, 2025
SGLT2 Inhibitors in CKD and Heart Failure: The Evidence That Changed Everything
Evidence Updates8 min

SGLT2 Inhibitors in CKD and Heart Failure: The Evidence That Changed Everything

From diabetes drugs to kidney and heart protectors — SGLT2 inhibitors have transformed nephrology and cardiology. Here is a concise summary of the landmark trials and how to apply them in your practice today.

Dr. James Okonkwo

Dr. James Okonkwo

December 28, 2024
MELD and MELD-Na: The Complete Guide to Liver Transplant Prioritisation
Clinical Guides7 min

MELD and MELD-Na: The Complete Guide to Liver Transplant Prioritisation

MELD-Na replaced standard MELD for organ allocation in 2016. Understand the formula, the sodium correction, and how to use these scores to guide transplant listing decisions and predict 90-day waitlist mortality.

Dr. Sarah Mitchell

Dr. Sarah Mitchell

December 22, 2024
Critical Drug Interactions: Anticoagulants and Antibiotics Every Clinician Must Know
Pharmacology9 min

Critical Drug Interactions: Anticoagulants and Antibiotics Every Clinician Must Know

Anticoagulant-antibiotic interactions are among the most clinically significant and frequently missed drug interactions. This guide covers warfarin, DOACs, and the antibiotics most likely to cause dangerous interactions.

Dr. Marcus Chen

Dr. Marcus Chen

December 18, 2024
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