Infectious Diseases

Antibiotic De-escalation Checklist

Assesses suitability for antibiotic de-escalation or stop at 48-72 hours (antimicrobial stewardship)

Share with colleagues

Input Parameters

All cultures negative after 48-72h

Clear clinical improvement (afebrile, improving WBC/CRP, haemodynamically stable)

Patient can take oral antibiotics and has functioning GI tract

Narrower-spectrum antibiotic available for identified pathogen

Source of infection controlled (drain placed, abscess drained, infected line removed)

Immunocompromised state (neutropenia ANC <500, high-dose steroids, post-transplant)

Clinical Note (Optional)

0/500 characters

Other evidence-based tools commonly used alongside this calculator

SOFA Score (Sepsis-3)

Sequential Organ Failure Assessment for sepsis diagnosis and ICU mortality prediction

Malaria Severity Assessment (WHO)

Classifies malaria severity per WHO 2015 criteria to guide IV vs. oral therapy

HIV/AIDS Staging & ART Eligibility

WHO clinical staging and ART eligibility assessment for HIV/AIDS

C. difficile Severity & Treatment

Classifies C. difficile infection severity (IDSA/SHEA 2021) and recommends treatment