Infectious Diseases

Antibiotic De-escalation Checklist

Assesses suitability for antibiotic de-escalation or stop at 48-72 hours (antimicrobial stewardship)

Share with colleagues

Input Parameters

All cultures negative after 48-72h

Clear clinical improvement (afebrile, improving WBC/CRP, haemodynamically stable)

Patient can take oral antibiotics and has functioning GI tract

Narrower-spectrum antibiotic available for identified pathogen

Source of infection controlled (drain placed, abscess drained, infected line removed)

Immunocompromised state (neutropenia ANC <500, high-dose steroids, post-transplant)

Clinical Note (Optional)

0/500 characters

Other evidence-based tools commonly used alongside this calculator

Pneumonia Severity Index (PORT/PSI)

Risk-stratifies CAP patients into five classes for site-of-care decisions

Vancomycin Dosing (AUC-based)

Calculates initial vancomycin dose targeting AUC/MIC 400-600 per ASHP/IDSA 2020 guidelines

UTI Severity & Treatment Guide

Classifies UTI severity and recommends empiric antibiotics based on risk factors

MRSA Risk Stratification

Predicts likelihood of MRSA infection to guide empiric antibiotic selection