Find answers to common questions about ClinicalCalc Pro, our medical calculators, data privacy, and more.
ClinicalCalc Pro is an evidence-based clinical decision support platform designed exclusively for physicians, residents, medical students, and healthcare professionals. It provides 432+ validated medical calculators across 27 specialties, drug interaction checking, clinical workflows, and more — all built to integrate seamlessly into your clinical practice.
Yes, ClinicalCalc Pro is completely free for all healthcare professionals. There are no hidden fees, premium tiers, or paywalls. Every calculator, workflow, and tool on the platform is accessible at no cost. Our mission is to support better clinical decision-making for all practitioners.
Simply visit the homepage and start using any calculator immediately — no registration required. You can browse calculators by specialty, search by name, or explore our curated workflows. For a personalized experience, you can save favorites, track calculation history, and create custom categories.
Absolutely. ClinicalCalc Pro is a Progressive Web App (PWA), which means you can install it directly from your browser on any device — iOS, Android, or desktop. Once installed, it works like a native app with offline support, so you can access calculators even without an internet connection during rounds or in areas with poor connectivity.
The platform currently offers 432+ clinical calculators spanning 27 medical specialties, including Cardiology, Nephrology, Neurology, Emergency Medicine, Pulmonology, Gastroenterology, Hematology, Oncology, Pediatrics, Geriatrics, ICU/Critical Care, Endocrinology, Rheumatology, Psychiatry, Obstetrics, Orthopedics, Urology, Dermatology, Ophthalmology, ENT, Infectious Disease, Anesthesiology, Radiology, Neonatology, and more.
Super Calculators are advanced clinical decision support systems that combine multiple related calculators into a single comprehensive tool. For example, the CKD Super Calculator integrates eGFR calculation, KDIGO staging, Kidney Failure Risk Equation, and management recommendations — all in one unified interface with guideline-based pathways. They are designed for complex clinical scenarios requiring multi-step assessment.
Clinical Workflows are guided, step-by-step decision pathways that chain multiple related calculators together in a logical clinical sequence. Unlike individual calculators, workflows walk you through an entire clinical assessment — for example, a Chest Pain Evaluation workflow might guide you through HEART Score, TIMI Risk, Wells PE Score, and appropriate next steps based on results. They include decision nodes, branching logic, and evidence-based recommendations at each step.
Yes. The Compare feature allows you to run multiple calculators simultaneously and view their results side by side. This is particularly useful when you need to cross-reference scoring systems — for example, comparing CHA₂DS₂-VASc with HAS-BLED for atrial fibrillation management, or comparing different GFR estimation equations.
Every calculator on ClinicalCalc Pro is built directly from peer-reviewed medical literature and validated against published clinical guidelines. The formulas are cross-referenced with original research papers, and results are tested against known reference values. We follow a rigorous development process that includes formula verification, edge-case testing, and periodic review to ensure alignment with the latest evidence.
We continuously monitor major medical journals, guideline updates, and clinical practice changes. When new evidence emerges that affects a calculator's formula, interpretation, or clinical recommendations, we update the tool promptly. Each calculator includes references to its source literature so you can verify the underlying evidence yourself.
No. ClinicalCalc Pro is a clinical decision support tool, not a replacement for clinical judgment. All results should be interpreted within the full clinical context, including patient history, physical examination, laboratory findings, and institutional protocols. The platform is designed to assist — not replace — the expertise of qualified healthcare professionals. Always verify critical calculations and consult specialist guidelines when appropriate.
Our drug interaction checker covers a curated database of clinically significant drug-drug interactions with severity classifications (major, moderate, minor) and actionable clinical recommendations. While it covers the most commonly encountered interactions in clinical practice, it is not a substitute for a comprehensive pharmacy database. For complex polypharmacy cases, we recommend cross-referencing with your institution's pharmacy resources.
Yes. You can mark any calculator as a favorite by clicking the heart icon. All your favorites are accessible from the dedicated Favorites page for quick access. You can also create Custom Categories to organize calculators by your own clinical workflows, patient populations, or rotation schedules.
Yes. Every calculation you perform is automatically logged with a timestamp, the input values used, and the result. You can add clinical notes to any calculation for documentation purposes. The full history is searchable, filterable by date and calculator type, and exportable in CSV or JSON format for medical records or case presentations.
The Unit Converter provides quick, accurate conversions between common medical units — including lab values (mg/dL to mmol/L), weight (kg to lbs), height (cm to inches), temperature (°C to °F), and many more. It's designed for the specific unit conversions healthcare professionals encounter daily.
Yes. ClinicalCalc Pro supports full data export and backup. You can export your calculation history, favorites, custom categories, and quick notes. The backup feature allows you to save and restore your entire configuration, ensuring you never lose your personalized setup even if you switch devices.
Yes. ClinicalCalc Pro stores your calculation data locally on your device by default, meaning your clinical data never leaves your device unless you explicitly choose to back it up. When cloud backup is used, data is encrypted and stored securely using industry-standard encryption protocols. We do not sell, share, or monetize any user data.
No. ClinicalCalc Pro does not collect, store, or transmit any patient-identifiable information. The calculators work with clinical parameters (lab values, vital signs, scores) without any patient identifiers. Any notes you add to calculations are stored locally on your device and are entirely under your control.
ClinicalCalc Pro is designed with privacy-first principles. Since the platform does not collect or transmit patient-identifiable health information, it operates outside the scope of HIPAA-covered activities. All calculation data is processed locally on your device. However, as with any clinical tool, users should follow their institution's policies regarding the use of clinical decision support tools.
Yes. As a Progressive Web App, ClinicalCalc Pro caches all calculator data and functionality for offline use. Once you've visited the site, you can access all calculators, your favorites, history, and tools without an internet connection. This is especially useful during hospital rounds, in rural clinics, or in areas with unreliable connectivity.
ClinicalCalc Pro works on all modern browsers including Chrome, Safari, Firefox, and Edge on both desktop and mobile devices. The responsive design adapts to any screen size — from large desktop monitors to smartphones. For the best experience, we recommend using the latest version of Chrome or Safari.
A Progressive Web App approach allows us to deliver a native-like experience across all platforms (iOS, Android, Windows, Mac) from a single codebase. This means faster updates, consistent features across devices, no app store downloads required, and the ability to work offline. You can still install it to your home screen for instant access, just like a native app.
Absolutely. We offer an Institutional Pilot Program for teaching hospitals, medical schools, and healthcare organizations. This includes customizable calculator sets aligned with your institutional protocols, usage analytics for program evaluation, dedicated technical support, and training resources for clinical staff. Contact us at pilot@clinicalcalc.pro to learn more.
Yes. Through our Institutional Pilot Program, we can customize calculator sets, adjust reference ranges, and align clinical recommendations with your institution's specific protocols and guidelines. This ensures the platform integrates seamlessly with your existing clinical workflows and standards of care.
Yes. Institutional accounts have access to a comprehensive analytics dashboard showing calculator usage patterns, adoption metrics, most-used tools by department, and engagement trends. These insights help program directors evaluate the platform's impact on clinical education and workflow efficiency.
We welcome feedback from all users. You can reach our team at support@clinicalcalc.pro with suggestions, bug reports, or requests for new calculators. Institutional partners have a dedicated feedback channel for priority feature requests. Many of our calculators have been added based on direct requests from practicing clinicians.
The CHA₂DS₂-VASc score assigns points for: Congestive heart failure (1), Hypertension (1), Age ≥75 years (2), Diabetes mellitus (1), Stroke/TIA history (2), Vascular disease (1), Age 65–74 years (1), and female Sex (1). Maximum score is 9. A score ≥2 in men or ≥3 in women indicates high stroke risk and warrants anticoagulation in atrial fibrillation. Score 1 in men or 2 in women: consider anticoagulation. Score 0 in men or 1 in women: anticoagulation not recommended.
The Sequential Organ Failure Assessment (SOFA) score quantifies organ dysfunction in ICU patients across 6 systems: Respiratory (PaO₂/FiO₂ ratio), Coagulation (platelets), Liver (bilirubin), Cardiovascular (MAP or vasopressors), CNS (GCS), and Renal (creatinine or urine output). Each system is scored 0–4. Total score 0–6: low mortality (<10%); 7–9: ~15–20%; 10–12: ~40–50%; 13–14: ~50–60%; 15: >80%; 15–24: >90%. A SOFA score ≥2 points above baseline defines sepsis-associated organ dysfunction per Sepsis-3 criteria.
eGFR (estimated Glomerular Filtration Rate) is most commonly calculated using the CKD-EPI 2021 equation, which uses serum creatinine, age, and sex (race-free). CKD stages by eGFR: G1 ≥90 mL/min/1.73m² (normal/high), G2 60–89 (mildly decreased), G3a 45–59 (mild-moderately decreased), G3b 30–44 (moderately-severely decreased), G4 15–29 (severely decreased), G5 <15 (kidney failure). Staging also incorporates albuminuria (A1/A2/A3) for full KDIGO risk classification. eGFR <60 for >3 months confirms CKD.
The Wells DVT Score estimates pre-test probability of deep vein thrombosis. Points are assigned for: active cancer (1), paralysis/paresis/immobilisation (1), bedridden >3 days or major surgery within 12 weeks (1), localised tenderness along deep venous system (1), entire leg swollen (1), calf swelling >3 cm vs. other leg (1), pitting oedema (1), collateral superficial veins (1), previous DVT (1), and alternative diagnosis at least as likely (−2). Score ≥2: high probability — proceed to ultrasound. Score <2: low probability — D-dimer testing first; if negative, DVT excluded.
The HEART Score stratifies risk of major adverse cardiac events (MACE) in chest pain patients. Five components scored 0–2 each: History (highly suspicious = 2, moderately suspicious = 1, slightly suspicious = 0), ECG (significant ST depression = 2, non-specific repolarisation = 1, normal = 0), Age (≥65 = 2, 45–64 = 1, <45 = 0), Risk factors (≥3 or history of atherosclerosis = 2, 1–2 risk factors = 1, none = 0), Troponin (>3× normal = 2, 1–3× normal = 1, ≤normal = 0). Score 0–3: low risk (MACE <2%) — consider early discharge. Score 4–6: moderate risk — observe and serial troponins. Score 7–10: high risk (MACE >50%) — early invasive strategy.
The Glasgow Coma Scale (GCS) assesses level of consciousness using three components. Eye Opening (E): Spontaneous = 4, To voice = 3, To pain = 2, None = 1. Verbal Response (V): Oriented = 5, Confused = 4, Inappropriate words = 3, Incomprehensible sounds = 2, None = 1. Motor Response (M): Obeys commands = 6, Localises pain = 5, Withdraws = 4, Abnormal flexion = 3, Extension = 2, None = 1. Total GCS = E + V + M (range 3–15). GCS ≤8 indicates severe brain injury and typically warrants airway protection. GCS 9–12: moderate injury. GCS 13–15: mild injury.
CURB-65 scores one point each for: Confusion (new disorientation), Urea >7 mmol/L (BUN >19 mg/dL), Respiratory rate ≥30/min, Blood pressure systolic <90 mmHg or diastolic ≤60 mmHg, and Age ≥65 years. Score 0–1: low severity — outpatient treatment appropriate (30-day mortality ~1.5%). Score 2: moderate severity — consider short inpatient stay or supervised outpatient (mortality ~9.2%). Score 3–5: high severity — hospitalise, consider ICU for score ≥4 (mortality 22–57%). CURB-65 is validated for community-acquired pneumonia in adults.
The Child-Pugh score assesses severity of chronic liver disease using five parameters, each scored 1–3: Bilirubin (μmol/L: <34 = 1, 34–50 = 2, >50 = 3), Albumin (g/L: >35 = 1, 28–35 = 2, <28 = 3), INR (<1.7 = 1, 1.7–2.3 = 2, >2.3 = 3), Ascites (none = 1, mild = 2, moderate-severe = 3), Hepatic encephalopathy (none = 1, grade I–II = 2, grade III–IV = 3). Class A (5–6 points): well-compensated, 1-year survival ~100%. Class B (7–9): significant functional compromise, ~80%. Class C (10–15): decompensated, ~45%. Class C is a common threshold for liver transplant listing.
Anion Gap (AG) = Na⁺ − (Cl⁻ + HCO₃⁻). Normal range: 8–12 mEq/L (without albumin correction) or 3–11 mEq/L (albumin-corrected). Albumin-corrected AG = measured AG + 2.5 × (4.0 − albumin in g/dL). An elevated AG (>12 mEq/L) indicates unmeasured anions and suggests: Methanol, Uraemia, Diabetic ketoacidosis, Propylene glycol, Isoniazid/Iron, Lactic acidosis, Ethylene glycol, Salicylates (mnemonic: MUDPILES). A normal AG metabolic acidosis suggests hyperchloraemic causes: GI bicarbonate loss (diarrhoea), renal tubular acidosis, or saline administration.
The Acute Physiology and Chronic Health Evaluation II (APACHE II) score predicts ICU mortality risk using 12 acute physiological variables (temperature, MAP, heart rate, respiratory rate, oxygenation, arterial pH, sodium, potassium, creatinine, haematocrit, WBC, GCS), age points, and chronic health points. Score range: 0–71. Score <10: predicted mortality ~4%. Score 10–19: ~15%. Score 20–29: ~40%. Score 30–34: ~55%. Score ≥35: >70%. APACHE II is used for ICU triage, benchmarking, and research stratification, not individual prognosis.
The Revised Cardiac Risk Index (Lee Index) predicts major cardiac complications after non-cardiac surgery. One point each for: High-risk surgery (intraperitoneal, intrathoracic, or suprainguinal vascular), History of ischaemic heart disease, History of congestive heart failure, History of cerebrovascular disease, Insulin-dependent diabetes mellitus, Pre-operative creatinine >2.0 mg/dL (177 μmol/L). Score 0: ~0.4% risk of MACE. Score 1: ~1%. Score 2: ~2.4–6.6%. Score ≥3: ~5.4–11%. Score ≥3 warrants cardiology consultation and consideration of pre-operative cardiac testing per ACC/AHA guidelines.
The Centor Score (modified McIsaac) estimates the probability of Group A Streptococcal pharyngitis. Points: Tonsillar exudate (1), Tender anterior cervical lymphadenopathy (1), Absence of cough (1), Fever >38°C (1), Age 3–14 years (+1), Age 15–44 years (0), Age ≥45 years (−1). Score ≤0: <10% GAS probability — no testing or antibiotics. Score 1: ~10% — no testing or antibiotics. Score 2–3: ~32% — throat culture or rapid antigen test; treat if positive. Score ≥4: >50% — empirical antibiotics may be considered. Antibiotic of choice: penicillin V or amoxicillin for 10 days.
The Padua Prediction Score assesses VTE risk in hospitalised medical patients. High-risk factors (3 points each): active cancer, previous VTE, reduced mobility ≥3 days, known thrombophilic condition. Moderate-risk factors (2 points): recent trauma/surgery within 1 month. Low-risk factors (1 point each): age ≥70, heart/respiratory failure, acute MI or ischaemic stroke, acute infection/rheumatological disorder, obesity (BMI ≥30), ongoing hormonal treatment. Score ≥4: high risk — pharmacological prophylaxis recommended (LMWH or UFH). Score <4: low risk — pharmacological prophylaxis not routinely recommended; consider mechanical prophylaxis.
The Model for End-Stage Liver Disease (MELD) score predicts 90-day mortality in patients with chronic liver disease. MELD = 3.78 × ln(bilirubin mg/dL) + 11.2 × ln(INR) + 9.57 × ln(creatinine mg/dL) + 6.43. MELD-Na adds serum sodium: MELD-Na = MELD + 1.32 × (137 − Na) − [0.033 × MELD × (137 − Na)]. Score <10: 1.9% 90-day mortality. Score 10–19: 6%. Score 20–29: 19.6%. Score 30–39: 52.6%. Score ≥40: 71.3%. UNOS uses MELD-Na ≥15 as the threshold for liver transplant listing priority. Scores are recalculated every 7–90 days depending on severity.
The Wells PE Score estimates pre-test probability of pulmonary embolism. Points: Clinical signs/symptoms of DVT (3), PE is #1 diagnosis or equally likely (3), Heart rate >100 bpm (1.5), Immobilisation ≥3 days or surgery in past 4 weeks (1.5), Previous DVT or PE (1.5), Haemoptysis (1), Malignancy treated within 6 months or palliative (1). Two-tier: Score >4 = PE likely (proceed to CT-PA); Score ≤4 = PE unlikely (D-dimer first; if negative, PE excluded). Three-tier: Score <2 = low probability (~2%); 2–6 = moderate (~17%); >6 = high (~65%). PERC rule can exclude PE without D-dimer if all 8 criteria are negative in low-probability patients.
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